GDNF complexed with GDF15, molecular model

GDNF complexed with GDF15, molecular model

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Caption: GDNF complexed with GDF15. Computer illustration showing a glial cell line-derived neurotrophic factor (GDNF) molecule (red) bound to a growth and differentiation factor 15 (GDF15) molecule (fuchsia) in a cell membrane (white) of the brainstem. GDF15 regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GDF15 levels increase in response to tissue stress and injury, and elevated levels are associated with body weight loss in numerous chronic human diseases.

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Keywords: artwork, biochemical, biochemistry, bound, brain stem, central nervous system, chemical, chemistry, cns, complex, complexed, energy, food intake, gdf15, gdnf, glial cell line-derived neurotrophic factor, growth and differentiation factor 15, growth-differentiation factor 15, illustration, injury, membrane, metabolic, metabolism, molecular, molecular model, molecule, molecules, no-one, nobody, protein, proteomics, quaternary structure, receptor, response, stress, stressed, tertiary structure, transforming growth factor beta

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