Chimeric antigen receptor on T-cell, illustration

Chimeric antigen receptor on T-cell, illustration

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Caption: Chimeric antigen receptor (CAR) on T-cell, illustration. The CAR structures are blue, with the cutaway foreground showing one spanning the cell membrane. These CARs are on the surface of an engineered T-cell. CARs are engineered cell receptors that allow T cells to recognize and attack cancer cells in a specific way. They are built by connecting several functional parts from different proteins. This receptor has a signal protein (ZAP70, purple, lower right) attached to the intracellular domain (bottom).

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