Cerivastatin cholesterol-lowering drug

Cerivastatin cholesterol-lowering drug

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Credit: DR MARK J. WINTER/SCIENCE PHOTO LIBRARY

Caption: Cerivastatin. Molecular model of the withdrawn cholesterol-lowering drug cerivastatin (Baycol). Atoms are represented as spheres and are colour-coded: carbon (dark grey), hydrogen (light grey), oxygen (red), nitrogen (blue) and fluorine (green). This drug is a type of statin. Statins are used to reduce the levels of low-density lipoprotein (LDL) cholesterol ('bad' cholesterol) in the bloodstream. High levels of LDL cholesterol are a major cause of heart disease and strokes. Cerivastatin was withdrawn by the manufacturer in 2001 due to a high occurence of fatal rhabdomyolysis, the rapid breakdown (lysis) of skeletal muscle.

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