Crohn's disease, light micrograph

Crohn's disease, light micrograph

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Caption: Crohn's disease. Light micrograph of a section through a large intestine affected by Crohn's disease, showing granulomata (pale regions, like that seen at lower left). A granuloma is a ball-like collections of immune cells that forms when the immune system attempts to wall off substances that it perceives as foreign but is unable to eliminate. Crohn's disease is a chronic inflammatory disorder of the intestines that causes ulceration and thickening of the lining.

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