Complicated atheroma, light micrograph

Complicated atheroma, light micrograph

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Caption: Fibrolipid plaque. Light micrograph of a section through a fibrolipid plaque in an artery affected by a complicated atheromatous lesion. Atheroma is the deposition of fatty material (lipids) on the inner walls of an artery. This deposit is known as a plaque. Once fibrous tissue develops in an atheromatous lesion it is called a fibrolipid plague. As the plaque enlarges, the blood supply to the vessel lining may be cut off leading to cell death (necrosis) and causing the surface to become ulcerated. This rough surface causes coagulation of the blood and the formation of a thrombus at the site of the ulcerated atheroma.

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