Insulin receptor substrate 1 molecule

Insulin receptor substrate 1 molecule

C003/0324 Rights Managed

Request low-res file

530 pixels on longest edge, unwatermarked

Request/Download high-res file

Uncompressed file size: 60.6MB

Downloadable file size: 875.6KB

Price image Pricing

Please login to use the price calculator


Credit: DR MARK J. WINTER/SCIENCE PHOTO LIBRARY

Caption: Insulin receptor substrate 1. Molecular model of the secondary structure of the protein insulin receptor substrate 1 (IRS1), bound to a molecule of phosphotyrosine (ball and stick molecule). This protein is phosphorylated by the insulin receptor, a transmembrane receptor. Phosphorylation of IRS1 leads to an increase in glucose transporter molecules on the membrane of insulin-responsive tissues, such as muscle and adipose (fat) tissue, and so an increase in glucose uptake. A decrease in the activity of the insulin receptor leads to type 2 diabetes.

Release details: Model release not available. Property release not required.

Keywords: alpha helix, artwork, beta sheet, beta sheets, biochemical, biochemistry, biological, biology, bound, chemistry, compound, compounds, cut out, cut outs, cut-out, cut-outs, cutout, cutouts, illustration, insulin receptor substrate 1, molecular, molecular model, molecule, phosphotyrosine, phosphotyrosine binding domain, protein, ptb, signal transducing, signal transduction, structure, type 2 diabetes mellitus, white background

Licence fees: A licence fee will be charged for any media (low or high resolution) used in your project.