Endothelin-1 molecule. Computer model showing the structure of a molecule of the protein endothelin-1 (EDN1). Atoms are colour-coded (carbon: grey, oxygen: red, sulphur: yellow, nitrogen: blue). Endothelins are proteins that constrict blood vessels (vasoconstriction) causing a rise in blood pressure. They are part of a system involved in maintaining stable conditions (homeostasis) within the vascular system. They can contribute to high blood pressure (hypertension) and heart disease if levels are too high.
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