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Ball-and-Stick Model of FT827

Ball-and-Stick Model of FT827

C044/0182

Rights Managed

36.0 MB (2.2 MB compressed)

4200 x 3000 pixels

35.6 x 25.4 cm ⏐ 14.0 x 10.0 in (300dpi)

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Credit

GREG WILLIAMS / SCIENCE SOURCE / SCIENCE PHOTO LIBRARY GREG WILLIAMS / SCIENCE SOURCE / SCIENCE PHOTO LIBRARY

Caption

FT827 is an inhibitor of the de-ubiquinating enzyme USP7. The figure shows a ball-and-stick model of FT827 in the catalytic cleft of the enzyme. The inhibitor forms a covalent isopeptide bond using the vinyl sulphonamide of FT827 and the catalytic Cys-223 residue of USP7.

Release details

Model release not required. Property release not required.

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