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MK-1775 tumour-suppressing inhibitor

MK-1775 tumour-suppressing inhibitor

C044/0186

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41.7 MB (1.6 MB compressed)

5400 x 2700 pixels

45.7 x 22.9 cm ⏐ 18.0 x 9.0 in (300dpi)

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Credit

GREG WILLIAMS / SCIENCE SOURCE / SCIENCE PHOTO LIBRARY GREG WILLIAMS / SCIENCE SOURCE / SCIENCE PHOTO LIBRARY

Caption

MK-1775 is a potent inhibitor of the tyrosine kinase enzyme Wee1. The Wee group of enzymes are negative regulators of the cell cycle via phosphorylation of critical enzymes that activate mitosis. MK-1775 enhances the cytotoxic effects of various anti-cancer drugs, including 5-fluorouricil. The compound is currently in Phase 2 clinical trials.

Release details

Model release not required. Property release not required.

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