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Histiocytic sarcoma, light micrograph

Histiocytic sarcoma, light micrograph

C046/8724

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50.0 MB (4.4 MB compressed)

4730 x 3695 pixels

40.1 x 31.2 cm ⏐ 15.8 x 12.3 in (300dpi)

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WEBPATHOLOGY / SCIENCE PHOTO LIBRARY WEBPATHOLOGY / SCIENCE PHOTO LIBRARY

Caption

Hairy cell leukaemia, light micrograph. Histiocytic sarcoma is a malignant tumour with histiocytic differentiation. It shows a diffuse growth pattern with partial or total effacement of the native architecture by a proliferation of high-grade malignant cells resembling histiocytes. The degree of pleomorphism is variable and mitotic activity is increased. The background stroma contains small lymphocytes, plasma cells, eosinophils, and benign histiocytes.

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