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GCSF hormone binding to membrane receptor, illustration

GCSF hormone binding to membrane receptor, illustration

C047/7827

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50.0 MB (1.7 MB compressed)

4827 x 3620 pixels

40.9 x 30.7 cm ⏐ 16.1 x 12.1 in (300dpi)

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Credit

RAMON ANDRADE 3DCIENCIA / SCIENCE PHOTO LIBRARY RAMON ANDRADE 3DCIENCIA / SCIENCE PHOTO LIBRARY

Caption

GCSF hormone binding to membrane receptor, illustration. Granulocyte colony-stimulating factor (GCSF, red) is a glycoprotein that acts as a hormone, and is the principal growth factor regulating the maturation, proliferation and differentiation of neutrophilic granulocytes in the bone marrow. This chemical can be used to treat neutropenia (a low concentration of a certain type of white blood cell), particularly as a side-effect of chemotherapy for cancer treatment. GCSF binds to its cytokine receptor (yellow), forming the gp130-type receptor-ligand complex shown here.

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