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Discoid lupus erythematosus lesion on the back of a 50-year-old man. The autoimmune disorder discoid lupus erythematosus (DLE) is a condition where the immune system attacks connective tissue as if it were foreign tissue. DLE causes periodically-recurring inflammation and scarring in a defined area. Sunlight can start an attack, though the underlying cause is unknown and there is no cure. The symptoms can be treated with anti-inflammatory drugs.
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