This image is not available for purchase in your country.

Activation of rhodopsin by light, molecular model

Activation of rhodopsin by light, molecular model

F033/4185

Royalty Free

137.3 MB (10.9 MB compressed)

8000 x 6000 pixels

67.8 x 50.8 cm ⏐ 26.7 x 20.0 in (300dpi)

This image is not available for purchase in your country.

Please contact your Account Manager if you have any query.

Credit

JUAN GAERTNER / SCIENCE PHOTO LIBRARY JUAN GAERTNER / SCIENCE PHOTO LIBRARY

Caption

Molecular model showing the activation of rhodopsin (purple, left) by light in a photoreceptor cell. Rhodopsin is a light sensitive G-protein coupled receptor (GPCR) with retinal (orange, top left) as a cofactor. When light hits rhodopsin, this causes a change in shape in retinal. This stimulates the G-protein transducin (blue), causing its alpha subunit (light blue) to exchange its bound molecule of GDP (guanosine diphosphate) for a molecule of GTP (guanosine triphosphate). This releases the alpha subunit, allowing it to activate the enzyme phosphodiesterase (PDE6). Phosphodiesterase hydrolyses cGMP, decreasing cGMP levels. This leads to the closing of sodium channels causing the outer segment membrane of the photoreceptor cell to become hyperpolarised.

Release details

Model release not required. Property release not required.

 {{ i.shot_duration ? i.shot_duration + ' ' : '' }}{{ i.shot_uhd ? '4K ' : i.hires ? 'HD ' : '' }}{{ i.spl_number }} R{{ i.license }}

  • basket icon
  • Calculate price calculator icon
  • Add to board lightbox icon