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Nevoid basal cell carcinoma syndrome, light micrograph

Nevoid basal cell carcinoma syndrome, light micrograph

C052/4969

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50.9 MB (19.2 MB compressed)

5104 x 3485 pixels

43.2 x 29.5 cm ⏐ 17.0 x 11.6 in (300dpi)

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Credit

NIGEL DOWNER / SCIENCE PHOTO LIBRARY NIGEL DOWNER / SCIENCE PHOTO LIBRARY

Caption

Light micrograph of a section through human skin showing nevoid basal cell carcinoma syndrome (NBCCS). This rare complex genetic disorder is characterised by a wide variety of developmental abnormalities and a predisposition to developing certain forms of cancer. It can be described as a particular type of skin cancer known as basal cell carcinoma. Nevoid basal cell carcinoma syndrome is caused by changes in one of three genes known as PTCH1, PTCH2 or SUFU.

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