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Immune response to inflammatory bowel disease, illustration

Immune response to inflammatory bowel disease, illustration

C052/7559

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67.3 MB (5.0 MB compressed)

5600 x 4198 pixels

47.5 x 35.6 cm ⏐ 18.7 x 14.0 in (300dpi)

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Credit

KEITH CHAMBERS / SCIENCE PHOTO LIBRARY KEITH CHAMBERS / SCIENCE PHOTO LIBRARY

Caption

Immune response to inflammatory bowel disease (IBD), illustration. IBD is a group of inflammatory diseases of the gut, including Crohn's disease and ulcerative colitis. Here, a tolerogenic dendritic cell (green, right) is seen releasing anti-inflammatory cytokine (signalling molecule) interleukin-10 (IL10, purple). Dendritic cells are immune cells that present pathogens or foreign molecules (antigens) to other cells of the immune system to be eliminated. Tolerogenic dendritic cells (tDCs) are dendritic cells with immuno-suppressive properties that produce a tolerance against antigens so cells do not attack the body's own cells and tissue. One way it can produce tolerance is by inducing normal T-cells (upper right) into regulatory T-cells (Treg) by releasing cytokine IL-10. T lymphocytes, or T cells, are a type of white blood cell and a component of the body's immune system. They recognise a specific site on the surface of a pathogen or foreign object (antigen), bind to it and attract antibodies or cells to eliminate it. Regulatory T cells can suppress responses by T cells to maintain homeostasis in the immune system.

Release details

Model release not required. Property release not required.

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