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Synthesis of interleukin-2 by E.coli bacterium

Synthesis of interleukin-2 by E.coli bacterium

B230/0044

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Credit

CNRI / SCIENCE PHOTO LIBRARY PHOTO LIBRARY CNRI / SCIENCE PHOTO LIBRARY PHOTO LIBRARY

Caption

False-colour transmission electron micrograph (TEM) showing the bacterium Escherichia coli, in the process of synthesising human Interleukin-2 (IL-2), a naturally-occuring cancer therapeutic. In this micrograph the pink inclusion body represents the IL-2. E. coli inhabits the human gut, where it is normally harmless. Under certain conditions, however, it may become pathogenic causing infections & diarrhoea. It is widely used in biotechnology & molecular genetics experiments, as here, in the mass production of a useful foreign substance. Magnification: x24, 000 at 6x7cm size.

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