LAGUNA DESIGN / SCIENCE PHOTO LIBRARY LAGUNA DESIGN / SCIENCE PHOTO LIBRARY
Enzyme catalysing DNA recombination. Computer model of the enzyme flippase recombinase (FLP recombinase, yellow, blue, orange and green) mediating the recombination of strands of DNA (deoxyribonucleic acid, green) at a Holliday Junction. This recombination is a natural genetic process known as crossing over, and involves the mixing of two strands of DNA. Recombinase enzymes snip open each DNA strand, starting the process going and forming a four-way alignment known as a Holliday Junction (at centre). This enzyme acts as both a ligase (bond-forming enzyme) and a lyase (bond-breaking enzyme).
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