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Artwork of adenoviruses carrying a gene transplant

Artwork of adenoviruses carrying a gene transplant

G200/0075

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Credit

KENNETH EWARD / BIOGRAFX / SCIENCE PHOTO LIBRARY KENNETH EWARD / BIOGRAFX / SCIENCE PHOTO LIBRARY

Caption

Adenovirus gene therapy. Artwork showing an adeno- virus (white, lower centre) binding to a structure (magenta) on a human cell (lower frame) so it can transplant genetically engineered genes into it. Adenoviruses are non-enveloped DNA viruses which infect mammals and birds. They can be engineered to carry human genes, and by infecting cells with these "recombinant" viruses, the genes are transplanted into cell DNA. Researchers may use gene implantation by a virus to study genetic diseases such as muscular dystrophy, haemophilia or cancer. The transplantation of healthy genes genetic diseases such as cystic fibrosis.

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