KENNETH EWARD / BIOGRAFX / SCIENCE PHOTO LIBRARY KENNETH EWARD / BIOGRAFX / SCIENCE PHOTO LIBRARY
Shown here are the DNA-binding regions of the p53 tumor suppressor protein, bound to DNA. Protein p53 is an important checkpoint in the cell cycle, ensuring the integrity of DNA replication. Defects of p53 are implicated in 50% of all cancers.
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