JAMES KING-HOLMES / ICRF / SCIENCE PHOTO LIBRARY JAMES KING-HOLMES / ICRF / SCIENCE PHOTO LIBRARY
Cytogeneticist arranging photo- graphs of human chromosomes (karyotyping) for diagnostic purposes. A karyotype is a document of the full complement of chromosomes in a somatic (non-sex) cell, arranged in numbered homologous pairs. The chromosomes are stained & photographed through a light microscope during the metaphase stage of cell division. A print of the photograph is cut up & arranged as a set of pairs of chromo- somes to facilitate comparison of the structures; any abnormalities of number or structure may give rise to defects in the individual (such as Down's Syndrome and some leukaemias).
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