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Gene therapy: microinjection of DNA into T-cell

Gene therapy: microinjection of DNA into T-cell

G210/0352

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Credit

PHILIPPE PLAILLY / SCIENCE PHOTO LIBRARY PHILIPPE PLAILLY / SCIENCE PHOTO LIBRARY

Caption

Gene therapy. DNA micro-injection technique, using a micropipette to introduce a corrective gene into a human T-lymphocyte (T-cell). The tip of the pipette (seen here) is manipulated by remote control using a joystick & viewed through a video camera attached to a microscope. This case involved a young girl whose immune system had collapsed because of her failure to produce an enzyme, adenosine desaminase (ADA), which controls the maturation of T-cells. Lymphocytes collected from her are treated with the gene that expresses ADA & the modified cells re-injected into a vein. Results are very good. Photo taken at Curie Institue, Orsay, France.

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Model release not required. Property release not required.

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