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DNA sequence charts used to study colour blindness

DNA sequence charts used to study colour blindness

G210/0535

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Credit

JAMES KING-HOLMES / SCIENCE PHOTO LIBRARY JAMES KING-HOLMES / SCIENCE PHOTO LIBRARY

Caption

DNA sequence charts. DNA sequence charts used to identify the colour-blindness gene in DNA obtained from the 150-year-old preserved eyeballs of English chemist John Dalton (1766-1844). Although best known for his atomic theory of matter, Dalton was also the first scientist to give a detailed account of colour blindness, based on his own confusion of red and green (Daltonism). His eyes were dissected after death, but no cause found. The preserved remains, however, enabled scientists in 1995 to recover Dalton's DNA and identify the mutant gene responsible. The black arrow shows the site of the mutation in the sequence of bases along the DNA. At top right are DNA sample tubes.

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