JAMES KING-HOLMES / AUTOMATION PARTNERSHIP / SCIENCE PHOTO LIBRARY JAMES KING-HOLMES / AUTOMATION PARTNERSHIP / SCIENCE PHOTO LIBRARY
Monoclonal antibody production. Technician with robotic machinery used to create monoclonal antibodies. Monoclonal antibodies are antibodies which all recognise the same substance. They are used in detecting viruses and other substances, for studying cell surface antigens, & in tissue-typing. They are made on a large scale by fusing antibody-producing cells (lymphocytes) with rapidly-multiplying myeloma (tumour) cells. The resulting hybridoma cells multiply in fermenters to produce large numbers of genetically identical copies, each secreting the antibody produced by the original lymphocyte.
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