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Tuberculosis colonies on dish in BCG vaccine study

Tuberculosis colonies on dish in BCG vaccine study

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Credit

H. RAGUET / EURELIOS / SCIENCE PHOTO LIBRARY H. RAGUET / EURELIOS / SCIENCE PHOTO LIBRARY

Caption

BCG vaccine research. Scientist researching a DNA bacille Calmette-Guerin (BCG) vaccine against TB (tuberculosis) examines a petri dish containing colonies of the TB-causing Mycobacterium organism. The scientist is part of a team led by Professor Content and Dr Huygen at the Brussels Pasteur Institute. A deoxyribonucleic acid (DNA) vaccine consists of purified DNA coding for a disease antigen. Here, a DNA vaccine coding for the TB antigen 85 has been tested in mice. Bacteria from the mice lungs & spleen are cultured and the colonies (circles) counted to determine vaccine effectiveness. This DNA vaccine could eventually provide important TB protection for humans.

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