NIBSC / SCIENCE PHOTO LIBRARY NIBSC / SCIENCE PHOTO LIBRARY
BCG vaccine testing. Coloured transmission electron micrograph (TEM) of a section through BCG vaccine (red, lower left) infecting a human macrophage white blood cell (green). BCG vaccines are live but attenuated (weakened) Mycobacterium bovis bacteria used to immunize patients against tuberculosis (TB). The bacteria sensitise the immune system to TB, so the body is prepared if the bacteria is encountered. This culture models the vaccine's effect in order to detect gene products from the macrophages it infects. It may be possible to use these products as a check of vaccination and to judge each vaccine's effective- ness. Magnification: x4,400 at 6x7cm size.
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