ANDY CRUMP / SCIENCE PHOTO LIBRARY ANDY CRUMP / SCIENCE PHOTO LIBRARY
Fluorescence molecular imaging system. This machine, the Olympus OV110, is an imaging system that allows high-sensitivity, high-speed imaging from individual cells to entire small animals (such as this mouse, red) through the use of fluorescent markers. The animal can be anaesthetised with isoflurane and kept at a constant temperature within the microscopy housing unit (at left) and viewed on the computer at right. The system has a zoom range of 105x and fluorescent imaging of the entire body, of organs, tissues or of individual cells can be conducted without disturbing the animal. The system requires a short exposure time and there are a variety of methods to label tissues, such as using fluorescent proteins or fluorescent probes.
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