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Sir Aaron Klug, British biochemist

Sir Aaron Klug, British biochemist

H411/0172

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Credit

JAMES KING-HOLMES / SCIENCE PHOTO LIBRARY JAMES KING-HOLMES / SCIENCE PHOTO LIBRARY

Caption

Aaron Klug. British molecular biologist Sir Aaron Klug (born 1926). He studied viruses and other biomolecules using crystallographic electron microscopy. He was awarded the Nobel Prize for Chemistry in 1982 for his work. He determined the structure of several DNA-protein complexes important in cell division. His team discovered the structure of zinc fingers, protein-metal ion complexes that bind to DNA and play a role in switching genes on and off. By designing specific zinc finger proteins, selected genes can be deactivated. This can be used to cure some cancers, such as leukaemia. Photographed in 1995.

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