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Evaluating DNA sequences of p53 anti-oncogene

Evaluating DNA sequences of p53 anti-oncogene

H413/0096

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Credit

PHILIPPE PLAILLY / SCIENCE PHOTO LIBRARY PHILIPPE PLAILLY / SCIENCE PHOTO LIBRARY

Caption

Research into tumour suppressor genes (anti- oncogenes). Professors Pierre & Evelyne May, of the French CNRS molecular oncology unit at Villejuif. The Mays are long-time researchers of p53, a protein discovered (in 1978) in cancer cells that was believed to boost their chaotic growth process. Subsequent research revealed that this particular p53 was abnormal, the product of a mutant gene (a corrupt set of genetic instructions) & that normal p53 serves to stop cells from becoming cancerous. It is also believed to prevent some potentially cancerous cells from dividing, & so prevent tumour formation.

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