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Charles Richet, French physiologist

Charles Richet, French physiologist

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Charles Robert Richet (1850-1935), French physiologist. Richet studied medicine in Paris and was appointed professor of physiology at the University of Paris, Sorbonne, in 1887. He initially explored various avenues of research, and in 1890, gave the first human injection of anti-tuberculosis serum. The growing use of antisera for the treatment of infectious diseases highlighted the problem of allergic reaction to injections. Richet studied this hypersensitivity in dogs. He concluded that repeated injections of foreign proteins over time eventually resulted in a fatal reaction, which he termed anaphylaxis. He was awarded the Nobel Prize for Medicine in 1913.

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