DR KLAUS BOLLER / SCIENCE PHOTO LIBRARY DR KLAUS BOLLER / SCIENCE PHOTO LIBRARY
Vaccinia virus particle. Coloured transmission electron micrograph (TEM) of a section through a vaccinia virus particle. The genetic core (red) is surrounded by membrane layers (green/yellow) taken from the host cell that replicated the virus. Vaccinia belongs to the orthopoxvirus group. Formation of new virus particles occurs in the cytoplasm of the host cell, whereas most other viruses replicate in the cell nucleus. The vaccinia virus causes cowpox, a disease of cattle and humans, which produces skin lesions. It was first used by Jenner in 1796 to protect against smallpox, a related but more deadly human disease, This is named vaccination. Magnification unknown.
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