EM UNIT, CVL, WEYBRIDGE / SCIENCE PHOTO LIBRARY EM UNIT, CVL, WEYBRIDGE / SCIENCE PHOTO LIBRARY
Transmission electron micrograph (TEM) of negative stained fibrils in an extract of fresh brain from a cow infected with bovine spongiform encephalopathy, a form of transmissible, slow virus encephalopathy. Human slow virus encephalopathies include Kuru, Creutzfeldt-Jakob disease and Gerstmann-Straussler syndrome. The agents causing these diseases form a group of virus-like organisms called prions. The fibrils are believed to be aggregations of the major proteins of the infectious agents themselves. Magnification: x205,000 at 6x8-inch size, x36,300 at 35mm size.
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