CNRI / SCIENCE PHOTO LIBRARY CNRI / SCIENCE PHOTO LIBRARY
Double-contrast barium X-ray showing the large intestine (colon) of a patient with Crohn's disease of the ileocaecal region, where the large & small intestines join (bottom left on image). Crohn's disease is a chronic inflammatory disease of unknown cause that mainly affects the small intestine, although the colon & anus may also be involved. Affected gut becomes thickened & pitted with fissured ulcers. Chronic disease may cause obstruction, leading to pain, diarrhoea & malabsorption (reduction in nutrient absorption). Complications include the formation of fistulae - abnormal junctions between bowel loops or surrounding tissues.
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