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Malfunctioning liver. Gross specimen of tissue from a liver affected by cholestasis, the blockage of bile production. The liver produces bile to aid fat digestion. It is passed from the liver to be stored in the gall bladder, and then released into the duodenum (the start of the small intestine) when required. Bile production is also necessary for the excretion of bile pigments. Jaundice, the yellowing of the skin and eyes, indicates a build- up of these bile pigments in the blood. Fat in the diet should be reduced, and fat-soluble vitamins (A, D, E, K) may need to be supplied. If the bile duct is blocked, surgery can remove the blockage.
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