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Crohn's disease, light micrograph

Crohn's disease, light micrograph

M130/0870

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Credit

ISM / SCIENCE PHOTO LIBRARY ISM / SCIENCE PHOTO LIBRARY

Caption

Crohn's disease. Light micrograph of a section through the colon epithelium of a patient with Crohn's disease. This is the tuberculoid form of the disease characterised by granulomas (inflamed nodules, dark pink oval at bottom right). Crohn's disease causes inflammation, thickening and ulceration of the digestive tract, most often the small intestine and the colon (large intestine). Its cause is unknown but may be linked to an overactive immune system. Symptoms include abdominal pain, diarrhoea and the malabsorption of food, leading to weight loss. Crohn's disease cannot be cured but can be controlled with anti- inflammatory drugs, nutritional supplements and occasionally surgery.

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