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Light micrograph of a human lymphoma, a cancerous tumour of lymph node cells or lymphocytes (dark stain dots) showing large quantities of collagen (turquoise), a fibrous protein found throughout the body. Collagen is produced by fibroblast cells whose elongated shape helps orientate the collagen into extended tracts which envelope & support soft tissues such as epithelium. In pathological conditions, as here, the dense & comparatively impenetrable nature of collagen serves to isolate small groups of tumour cells. The dense collagen pattern is indicative of a less malignant type of lymphoma. Magnification: x40 at 35mm size.
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