DR. E. WALKER / SCIENCE PHOTO LIBRARY DR. E. WALKER / SCIENCE PHOTO LIBRARY
Cancer of the large intestine. Light micrograph of an adenocarcinoma tumour from a patient with can- cer of the colon (large intestine) - one of the most common forms of cancer. Adenocarcinomas arise from glandular epithelial cells, such as mucus- secreting cells in the gut. The cancer cells here appear dark brown, stained by cytokeratin anti- body. The surrounding unstained material is connective tissue and blood vessels, the nuclei of which appear blue. Cytokeratin is a structural protein produced by epithelial cells. Cytokeratin antibody binds specifically to the protein, and is used to confirm the epithelial origin of unidenti- fied tumours. Magnification x125 at 35mm size.
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