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LM of biopsy cells showing adenocarcinoma

LM of biopsy cells showing adenocarcinoma

M132/0555

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Credit

PARVIZ M. POUR / SCIENCE PHOTO LIBRARY PARVIZ M. POUR / SCIENCE PHOTO LIBRARY

Caption

Adenocarcinoma cells. Light micrograph (LM) of a biopsy sample showing adenocarcinoma cells. An adenocarcinoma is a cancer arising from glandular tissue. The majority of the cells here have large, irregular, dividing nuclei (dark blue). The large cell at lower right has its nucleus displaced to one side by a large pale-staining vacuole. Cells such as these are known as "signet cells", from their supposed resemblance to signet rings. These secretory vacuoles are this sample's only evidence of the cancer's glandular origin. Carcinomas can be treated by chemotherapy and radiotherapy, or by surgery if they have not spread. Most are fatal. Papanicolaou stained. Magnification unknown.

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