27.4 MB (2.7 MB compressed)
2701 x 3543 pixels
22.9 x 30.0 cm ⏐ 9.0 x 11.8 in (300dpi)
HATTIE YOUNG / SCIENCE PHOTO LIBRARY HATTIE YOUNG / SCIENCE PHOTO LIBRARY
Down's syndrome. A four year old girl with Down's syndrome, also known as trisomy 21, playing with a toy. Down's syndrome results from a chromosomal abnormality; each body cell contains an extra chromosome (number 21) so that there are 47 chromosomes rather than the usual 46. This results in a variable mental handicap; IQ usually lies between 30 and 80 (almost all affected children have learning potential), and distinctive appearance with upward-sloping eyes. Heart defects, congenital deafness and leukaemia are more common in people with Down's syndrome. About one in 650 babies shows this abnormality & this rate increases with increased maternal age.
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