51.1 MB (3.5 MB compressed)
3664 x 4878 pixels
31.0 x 41.4 cm ⏐ 12.2 x 16.3 in (300dpi)
HATTIE YOUNG / SCIENCE PHOTO LIBRARY HATTIE YOUNG / SCIENCE PHOTO LIBRARY
Down's syndrome. A three year old girl with Down's syndrome, also known as trisomy 21, with bubbles. Down's syndrome results from a chromosomal abnormality; each body cell contains an extra chromosome (number 21) so that there are 47 chromosomes rather than the usual 46. This results in a variable mental handicap; IQ usually lies between 30 and 80 (almost all affected children have learning potential), and distinctive appearance with upward-sloping eyes. Heart defects, congenital deafness and leukaemia are more common in people with Down's syndrome. About one in 650 babies shows this abnormality & this rate increases with increased maternal age.
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