MARSEAUD, ISM / SCIENCE PHOTO LIBRARY MARSEAUD, ISM / SCIENCE PHOTO LIBRARY
Diabetes mellitus type 2. Computer artwork of malfunctional glucose metabolism in type 2 diabetes. Glucose (white) is a simple form of carbohydrate (sugar) that the body uses as energy. It is obtained from the digestion of food. Normally, when the glucose passes through the walls of the intestines (upper left) to the bloodstream a signal is sent to the pancreas (yellow, upper centre) to secrete the hormone insulin, which converts the glucose to glycogen for storage. Here, there is very little insulin, which encourages the liver (centre right) to release its stored glucose into the blood. The muscle cells (lower left) and adipose (fat) cells (lower right) have become less responsive to the insulin ('insulin resistance'). See P750/176 for a diagram showing the normal metabolism of glucose.
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