DR P. MARAZZI / SCIENCE PHOTO LIBRARY DR P. MARAZZI / SCIENCE PHOTO LIBRARY
Gangrene. Close-up of a toe affected by gangrene, in which tissue death (necrosis) has resulted in a blackening of the toe. The foot was affected by ischaemia: an insufficient supply of blood due to constriction or blockage of a blood vessel. As a result, tissues at the extremities of the foot were starved of oxygen. Ischaemic limbs are usually painful and pulseless. Ischaemia may be caused by atherosclerosis, narrowing of arteries due to deposits of fat. It may also result from an injury to a vessel or an inadequate blood flow due to inefficient pumping of the heart. Treatment includes vasodilator drugs or angioplasty, but gangrene may require surgical amputation.
Model release not required. Property release not required.