DR P. MARAZZI / SCIENCE PHOTO LIBRARY DR P. MARAZZI / SCIENCE PHOTO LIBRARY
Gangrenous leg. Gangrene (localised tissue death, black) resulting from an ulcer on the leg of a 77 year old woman with peripheral vascular disease (PVD). An ulcer is an open sore that does not heal and may turn necrotic, as seen here. PVD is a condition resulting from obstructed peripheral arteries, caused by underlying conditions such as atherosclerosis, stenosis, an embolism or a thrombus. PVD results in ischaemia (restricted blood supply), ulceration and gangrene. This gangrene was so bad that it required leg amputation. For the same patient's toes, see image M165/363.
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