ASTRID & HANNS-FRIEDER MICHLER / SCIENCE PHOTO LIBRARY ASTRID & HANNS-FRIEDER MICHLER / SCIENCE PHOTO LIBRARY
Light micrograph of a section of human liver affected by haemosiderosis, a condition characterized by the excessive deposition of iron in the liver and caused by a high dietary intake or following repeated blood transfusions. Iron is stored as haemosiderin in the Kuppfer cells and hepatocytes (liver cells) and causes liver cell death and cirrhosis. Here, some cells contain large quantities of iron which has been stained black. A comparable condition, haemochromatosis, results from an inherited defect in iron metabolism and affects other organs in addition to the liver. Magnification: x100 at 35mm size.
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