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Acute myocardial infarction. Sectioned gross specimen of the left ventricle of the human heart after acute myocardial infarction (heart attack). An area of necrosis (tissue death) is seen as the dark brown area (lower right). Normal heart tissue in this preserved ventricle is yellow. The tissue death resulted from a blockage (blood clot) in one of the two coronary arteries which provide the heart with its blood supply. As a result a region of heart muscle is starved of oxygen and it dies. The pumping rhythm of the heart is affected, and total heart failure may occur. Atherosclerosis (fatty plaques developing in arteries) usually causes clots to form, resulting in heart attack.
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