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Brittle bone disease

Brittle bone disease

M230/0345

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25.7 MB (1.9 MB compressed)

2406 x 3733 pixels

20.3 x 31.5 cm ⏐ 8.0 x 12.4 in (300dpi)

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Credit

DR M.A. ANSARY / SCIENCE PHOTO LIBRARY DR M.A. ANSARY / SCIENCE PHOTO LIBRARY

Caption

Brittle bone disease. Image 1 of 2. Patient with severe osteogenesis imperfecta (OI). OI is a brittle bone disorder, caused by a dominant genetic mutation of the gene for collagen, a vital protein found in bones. Sufferers either have too little, or have poor quality collagen. Consequently the skeleton is fragile and prone to multiple broken and fractured bones. In severe cases of OI, as here, the patient has a barrel-chest, spinal curvature, severe bone deformities, loose joints, and poor muscle development in the limbs. There is no treatment for OI. See M230/346 for a view of the same patient in profile.

Release details

Model release available. Property release not required.

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