ZEPHYR / SCIENCE PHOTO LIBRARY ZEPHYR / SCIENCE PHOTO LIBRARY
Paget's disease. Coloured X-ray of the skull of a sixty- five year old woman with Paget's disease. The skull has a mottled appearance due to malformation of the bone, and parts of the skull have become thickened, red . Paget's disease, or osteitis deformans, is a chronic bone disease that results in enlarged or deformed bones. The rate of bone reabsorption and formation increase and become out of balance, leading to structurally disorganised, weaker and enlarged bone. Treatment is not usually required, but can be with painkillers or bisphosphonates, which slow the abnormal process and promote growth of normal bone.
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