DR P. MARAZZI / SCIENCE PHOTO LIBRARY DR P. MARAZZI / SCIENCE PHOTO LIBRARY
Urticaria reaction. Itchy, red rash (weals) on the leg of a 45-year-old man. The weals are a symptom of urticaria, which has occured in response to the anti-depressant drug venlafaxine. Other factors, such as food or temperature, can cause an urticaria reaction. The drug has stimulated cells to release substances that cause small blood vessels to leak fluid into the skin. The resulting weals may last for a few minutes or several hours. Treatment is with antihistamines and avoidance of the cause.
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