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Chromosome spread of patient with cystic fibrosis

Chromosome spread of patient with cystic fibrosis

M352/0021

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Credit

J.C. REVY, ISM / SCIENCE PHOTO LIBRARY J.C. REVY, ISM / SCIENCE PHOTO LIBRARY

Caption

Cystic fibrosis chromosome spread. Coloured light micrograph showing a chromosome spread of a male patient with cystic fibrosis. The chromosomes are long thread like structures, with the nucleus of another cell at left. At upper right, the patient's pair of chromosome 7's are highlighted with an arrow. The code 7q11-q32 indicates the region on the chromosome where the mutation that causes cystic fibrosis is found. Cystic fibrosis is an inherited disorder that leads to chronic mucus production in the lungs. It is caused by a mutation in the gene that produces a protein known as CFTR. Molecular biologists have isolated and cloned this gene, paving the way for gene therapy.

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