JOHN BAVOSI / SCIENCE PHOTO LIBRARY JOHN BAVOSI / SCIENCE PHOTO LIBRARY
Endoscopic biopsy. Artwork of an endoscope (black) being used to remove a biopsy (tissue sample for histological testing) from a suspected cancer (brown, centre right) of the oesophagus. This oesophagus (gullet) is affected by Barrett's oesophagus. In this condition, the cells lining the lower oesophagus become similar to those which line the stomach (bottom), a change known as metaplasia. This is usually due to prolonged acid reflux, where stomach acid (yellow) enters the oesophagus. Barrett's oesophagus often leads to oesophageal carcinoma (cancer of the oesophagus). The endoscope is a fibre-optic cable which gives views of the body's interior.
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