This image is not available for purchase in your country.

Bacterial synthesis of human haemoglobin

Bacterial synthesis of human haemoglobin

M530/0220

Rights Managed

This image is not available for purchase in your country.

Please contact your Account Manager if you have any query.

Credit

DAVID PARKER / SCIENCE PHOTO LIBRARY DAVID PARKER / SCIENCE PHOTO LIBRARY

Caption

Synthesis of human haemoglobin for use as a blood substitute using recombinant DNA techniques. Scientists at the U.K. Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, and Somatogen Inc., in the U.S. have produced a synthetic haemoglobin, the oxygen-carrying molecule in blood, using genetic engineering techniques on the bacterium E. coli. The bottle at left (NC alpha) contains bacterial cells producing haemoglobin (red colour) whilst the one at right (TG-1) shows no presence of haemoglobin. The need to develop a blood substitute has arisen because of concern over contamination of stocks by pathogens such as HIV, the virus causing AIDS. Renal toxicity due to dissociation into dimers, overcome by expressing alpha chain as a fused dimer; assembly with 2 beta chains into stable dimers.

Release details

Model release not required. Property release not required.

 {{ i.shot_duration ? i.shot_duration + ' ' : '' }}{{ i.shot_uhd ? '4K ' : i.hires ? 'HD ' : '' }}{{ i.spl_number }} R{{ i.license }}

  • Add to board
  • Similar {{ mediaType(i) }}